A new scientific study has raised concerns about the effects of cannabis on women’s fertility, suggesting that the active compound in marijuana, THC, may directly impact egg quality and embryo development. The research, published in Nature Communications, provides the strongest evidence yet that cannabis use could influence reproductive health in women.

Researchers examined follicular fluid collected from women undergoing IVF treatment and found measurable levels of THC and its metabolites. While higher THC exposure was associated with oocyte maturation, it was also linked to lower rates of genetically normal embryos. This finding suggests that cannabis could increase the risk of chromosomal abnormalities during early reproductive stages.

Laboratory tests reinforced these observations. When immature human oocytes were exposed to THC, scientists noted abnormal spindle formations and errors in chromosome segregation. These disruptions are critical because they can compromise embryo viability and increase the chances of miscarriage.

The study marks the first time scientists have shown how cannabis interacts with female reproductive cells directly at the earliest stage. Until now, most discussions of cannabis and fertility have focused on pregnancy outcomes, but this research suggests potential impacts even before conception.

Experts caution that the findings do not mean all cannabis users will face infertility. Many women who consume marijuana are still able to conceive naturally. However, for those undergoing fertility treatments such as IVF, the study highlights the importance of careful medical guidance and awareness of potential risks.

As cannabis use continues to rise globally, these findings add to a growing body of research urging caution for individuals planning families. The results also raise new questions about how long-term or heavy cannabis use may influence reproductive health outcomes in women.

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